Actinomycin D for Wilm's tumor.
نویسندگان
چکیده
منابع مشابه
Actinomycin D in Wilms' Tumour: Treatment of Lung Metastases* By
This paper discusses recent world trends in the treatment of Wilms' tumour, particularly as exemplified by their impact on practice at the Royal Children's Hospital, Melbourne. Following the use of actinomycin D in the therapy of lung metastases of Wilms' tumour (see below), it became apparent that this drug was able, at times, to inhibit their growth and, more rarely, to cause their complete r...
متن کاملTreatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group.
OBJECTIVE We evaluated the use of alternating cycles of cyclophosphamide/etoposide and carboplatin/etoposide in children entered on National Wilms Tumor Study (NWTS)-5 who were diagnosed between August 1, 1995 and May 31, 2002 and who relapsed after chemotherapy with vincristine, actinomycin D, and doxorubicin (VAD) and radiation therapy (DD-4A). PATIENTS AND METHODS One hundred three patient...
متن کاملActinomycin D effects on nucleic acids during tumor regression.
Early effects of sublethal doses have been compared in sensitive Ridgway osteogenic sarcoma (ROS) and resistant (DMBA) tumors [designation for a spindle cell sarcoma orig inally induced in AKR mice with 7,12-dimethylbenz(o)anthracene] and in small intestine in mice. Doses of actinomycin which were tumoricidal for the sensitive tumor were also toxic to intestinal crypt cells; DNA synthesis, esti...
متن کاملMiR-21 Expression in Wilms’ Tumor
Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, in WT tissue samples which is a very common urinary tract malignancy in children...
متن کاملActinomycin D Effects on Nucleic Acids during Tumor Regression1
Early effects of sublethal doses have been compared in sensitive Ridgway osteogenic sarcoma (ROS) and resistant (DMBA) tumors [designation for a spindle cell sarcoma orig inally induced in AKR mice with 7,12-dimethylbenz(o)anthracene] and in small intestine in mice. Doses of actinomycin which were tumoricidal for the sensitive tumor were also toxic to intestinal crypt cells; DNA synthesis, esti...
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ژورنال
عنوان ژورنال: BMJ
سال: 1973
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5857.49-a